One John Marshall Drive

Robert C. Byrd Biotechnology Science Center, Suite 314

Huntington, WV 25755




Recent Updates


Progenesis receives an NIH Phase I SBIR Grant.  In September of 2015 Progenesis received a grant of $144,000 from the National Institute of General Medical Sciences through the Small Business Innovation Research (SBIR) Program.  The purpose of this award was to engineer a strain of Pseudomonas aeruginosa, that can under certain conditions infect humans, to remove potential toxic products and render it non-pathogenic.  This strain is needed to meet the concerns raised by the Center for Food Safety and Applied Nutrition of the FDA.  We have achieved 95% of the objectives set for this funded project, including demonstrating that this new engineered strain (PGN4) still produces a high amount of alginate.  The last task is to remove a gene critical for human infection.  We have already demonstrated that removal of this gene from the common laboratory strain P. aeruginosa PA01 totally prevents its ability to infect and cause death of mice.  The unmodified PA01 strain killed 70% of the mice within 24h after injection of the bacteria.


The Consulting Firm BBCetc Helps Progenesis Submit a Phase II SBIR Grant Application.  Once an applicant, such as Progenesis, has received a Phase I award, they are eligible to submit a Phase II grant application.  The purpose of the Phase II award is to aid in the commercialization of the innovative technology.  The amount of this award is substantial, up to $1million over a two-year period.  However, the application is more complex than the Phase I and requires up to a 12-page commercialization plan.  Therefore, Progenesis decided to engage the services of the consulting firm BBC entrepreneurial training & consulting. (BBCetc).  The company has an excellent track record in helping small business obtain SBIR funding.  Their stringent review and insightful suggestions were invaluable in the writing of this Phase II application.  The final version was submitted to the NIH prior to the September 5th 2016 deadline.  Our initial review score was promising and information about potential funding will be obtained in mid-February of 2017.


TechConnect WV’s ScaleUp program awards Progenesis $2,448.  In order to encourage small businesses in WV to submit more competitive SBIR grant applications, TechConnect WV initiated a Scale-Up program that pays for up to 75% of the cost for consultants to help in the writing and review of SBIR grants before they are submitted to the designated Federal Agency.  Progenesis applied for this award and with the help of Anne Barth, Executive Director of TechConnect WV, John Golden, Program Manager TechnConnect WV and Kevin DeGregorio Executive Director of the Chemical Alliance Zone, Progenesis application was approved for funding by the TechConnect WV Board.  We are much appreciative of the help and the confidence that TechConnect has provided for Progenesis.

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